Obesity body mass index euploid embryos miscarriage preimplantation genetic testing for aneuploidy.Ĭopyright © 2020 American Society for Reproductive Medicine. Women with obesity experience a higher rate of miscarriage after euploid embryo transfer than women with a normal weight, suggesting that other mechanisms than aneuploidy are responsible for this outcome. Obesity in women and day 6 trophectoderm biopsy were found to influence the reduced live birth rate. Live birth rates also were lower in women with obesity. Miscarriage rates were significantly higher in women with obesity compared to women with normal weight, mainly due to a significant increase in the clinical miscarriage rates. Fertilization rate, day of embryo biopsy, technique of chromosomal analysis, number of euploid embryos, number of transferred embryos, and method of endometrial preparation for embryo transfer were similar in the four BMI groups. The number of PGT-A cycles per patient was similar in the four groups. Secondary outcomes were implantation, pregnancy, clinical pregnancy, and live birth rates.Ĭycles were divided into four groups according to BMI (kg/m 2): underweight (<18.5 n = 155), normal weight (18.5-24.9 n = 2,549), overweight (25-29.9 n = 591), and obese (≥30 n = 185).
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The primary outcome was the miscarriage rate, which included both biochemical and clinical miscarriages. In this study, 3,480 cycles of in vitro fertilization with preimplantation genetic testing for aneuploidy (PGT-A) in the blastocyst stage and euploid embryo transfer were divided into four groups according to patient BMI. University-affiliated in vitro fertilization center. I am over quite overweight and Valencia have been very accommodating so far.
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I am 3 transfer donor eggs no more frozen left.
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There are only 2 flights a week from Manchester to Valencia. To determine whether female body mass index (BMI) is associated with an increased risk of miscarriage after euploid embryo transfer.Ī retrospective, observational, multicenter cohort study. I am thinking of moving from Valencia to Barcelona, purely for travelling purposes.